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RGDS peptide

CAS No. 91037-65-9

RGDS peptide ( Arg-Gly-Asp-Ser )

Catalog No. M16537 CAS No. 91037-65-9

RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    RGDS peptide
  • Note
    Research use only, not for human use.
  • Brief Description
    RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin.
  • Description
    RGDS peptide (Arg-Gly-Asp-Ser) is a integrin binding sequence that inhibits integrin receptor function, a tetrapeptide analogue of the cell attachment site of fibronectin; decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of inflammatory cytokines, iNOS and MMP-9; inhibits thrombin-induced binding of platelets to fibronectin, fibrinogen α, and von Willebrand factor with IC50 of 10 uM.
  • Synonyms
    Arg-Gly-Asp-Ser
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Integrin
  • Recptor
    Integrin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    91037-65-9
  • Formula Weight
    433.42
  • Molecular Formula
    C15H27N7O8
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 55 mg/mL
  • SMILES
    C(CC(C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)N)CN=C(N)N
  • Chemical Name
    L-Serine, L-arginylglycyl-L-α-aspartyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Grigoriou V, et al. J Biol Chem. 2005 Jan 21;280(3):1733-9.
2. Moon C, et al. Respir Res. 2009 Mar 9;10:18.
3. Droppelmann CA, et al. J Biol Chem. 2009 May 15;284(20):13551-61.
4. Gartner TK, et al. J Biol Chem. 1985 Oct 5;260(22):11891-4.
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